How Forces Fold the Cerebral Cortex
نویسندگان
چکیده
منابع مشابه
Clever space saving—how the cerebral cortex folds.
The human cerebral cortex controls complex cognitive behaviors. During mammalian evolution, the number of neurons increased in many lineages, requiring a larger cortical surface area to fit into a skull that did not scale proportionally. This space problem was solved by cortical folding, resulting in gyrencephalic (folded) brains. While several hypotheses have been proposed to explain cortical ...
متن کاملHow old is your fold?
MOTIVATION At present there exists no age estimate for the different protein structures found in nature. It has become clear from occurrence studies that different folds arose at different points in evolutionary time. An estimation of the age of different folds would be a starting point for many investigations into protein structure evolution: how we arrived at the set of folds we see today. It...
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Drug abuse has been claimed to cause the loss of neurons and reduction of volume in both the adult and developing brain. This study examined cortex volumes in cerebrum and cerebellum of male rats that were dependent on morphine using unbiased stereological counting methods and systematic random sampling technique. Our goal was to test whether short time exposure to morphine can affect the corte...
متن کاملHow do chaperonins fold protein?
Protein folding is a biological process that is essential for the proper functioning of proteins in all living organisms. In cells, many proteins require the assistance of molecular chaperones for their folding. Chaperonins belong to a class of molecular chaperones that have been extensively studied. However, the mechanism by which a chaperonin mediates the folding of proteins is still controve...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2018
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1105-17.2017